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Methylation Panel from Superpower

Labbrary Test GradeUseful
Your Fit Score
Not calculated

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Labbrary's review, Fit Score, and basic comparison are free. The provider's panel, shipping, collection, clinician review, and other services are separate. About 2 minutes. No account required.

Measures B-vitamin and homocysteine-related blood markers to help assess nutritional factors involved in methylation. The national version includes RBC folate; New York and New Jersey use a different version without it.

Current price
$149
Sample
Blood
Turnaround
Not confirmed
Access
Lab Visit, Membership, Order Online
Evidence & Key Facts
Source collectedLast source check September 8, 2026

Evidence basis. This named result reflects the sources and verification evidence listed on this page as of the date shown.

Best for

Methylation

Standout strength

Combines vitamin B12 with methylmalonic acid and homocysteine for complementary information about B-vitamin status.

Important watch-out

RBC folate is included nationally but omitted from the New York/New Jersey version. Confirm the version available for your address.

Methylation Panel from Superpower
Labbrary Test GradeUseful
Your Fit Score
Not calculated

Answer five questions to see how this panel matches your goals, budget, collection preferences, access, and support needs.

Calculate my fit

Labbrary's review, Fit Score, and basic comparison are free. The provider's panel, shipping, collection, clinician review, and other services are separate. About 2 minutes. No account required.

Measures B-vitamin and homocysteine-related blood markers to help assess nutritional factors involved in methylation. The national version includes RBC folate; New York and New Jersey use a different version without it.

Current price
$149
Sample
Blood
Turnaround
Not confirmed
Access
Lab Visit, Membership, Order Online
Evidence & Key Facts
Source collectedLast source check September 8, 2026

Evidence basis. This named result reflects the sources and verification evidence listed on this page as of the date shown.

Best for

Methylation

Standout strength

Combines vitamin B12 with methylmalonic acid and homocysteine for complementary information about B-vitamin status.

Important watch-out

RBC folate is included nationally but omitted from the New York/New Jersey version. Confirm the version available for your address.

Labbrary+

The Test Grade. The Reason Behind It.

Potentially useful for the right buyer, with meaningful evidence, coverage, transparency, access, cost, terms, or privacy tradeoffs to review.

A lower grade does not mean a panel is a bad personal fit. Your Fit Score can be higher when its purpose, price, sample, access, or support matches what you need.

Explore the Full Methodology
Labbrary Test GradeUseful

Next step

Check the panel or research the provider

Prices, availability, and ordering requirements can change. Confirm the current details before purchasing.

View Exact Panel on Provider SiteView Superpower profile

Scope, both directions

Inside the Panel. Beyond the Name.

Named measurements

  • Vitamin B12 (national and New York/New Jersey versions)
  • RBC Folate (national version only)
  • Homocysteine (national and New York/New Jersey versions)
  • Methylmalonic Acid (national and New York/New Jersey versions)
  • Vitamin B6 (national and New York/New Jersey versions)

Measured categories and focus areas

  • General Health
  • Methylation

Important limits and omissions

  • Complete unavoidable charges, membership applicability and product-specific refund terms remain unconfirmed.
  • Collection frequency, specific preparation steps and an exact turnaround range remain unconfirmed.
  • Individual assay performance, report decision thresholds and product-specific specimen retention remain unconfirmed.

The full breakdown

Eight Dimensions.
One Named Result.

Open any row for the reasoning and evidence behind the named result.

The exact offer page states this panel is processed by Quest Diagnostics and describes its assays as FDA-cleared clinical laboratory assays performed in CLIA-certified, CAP-accredited laboratories. The page does not publish assay precision data, reference-interval validation, or per-biomarker performance figures.

The exact offer page describes this panel for people investigating methylation-cycle issues such as MTHFR variants, homocysteine, fatigue, or brain fog. It does not publish clinical guidelines or eligibility criteria beyond the page description.

The Biomarkers tested section on the exact offer page names each marker in the panel, including vitamin B12 and red blood cell folate. No additional markers are referenced elsewhere on the page.

The exact offer page states results are typically ready in about a week and land in the Superpower app, and that results are interpreted by clinicians in context rather than as a stand-alone diagnosis. The page does not publish sample reports or reference intervals.

The exact offer page identifies Superpower as the provider, states the panel is processed by Quest Diagnostics, and gives its regulatory status (FDA-cleared assay or laboratory-developed test validated under CLIA). Corporate ownership, full terms of service, and lab credentials beyond the stated certification are not published on the page.

The exact offer page states the panel is available in 40 states and is not offered in New York or New Jersey, with collection in person at Quest Diagnostics. Residents of excluded states cannot order it.

The exact offer page lists the panel at $149, and Superpower requires a $349 annual membership in addition to the panel price. Refund and cancellation terms for the panel itself are not published on the page.

Superpower publishes a privacy policy covering the service, and the panel page notes results are delivered through the Superpower app. The page does not publish a panel-specific data-handling statement, so how this panel's samples and data are stored, shared, or deleted beyond the general policy is not documented.

What it asks of you

Sample and fulfillment journey

Order

Confirmed

Order online and confirm the regional version, address eligibility and applicable membership charges before paying.

Panel-specific source · Source dated September 8, 2026

Collect

Confirmed

Attend a professional blood collection appointment. Preparation instructions are provided when booking; confirm any fasting requirements and collection frequency.

Panel-specific source · Source dated September 8, 2026

Report

Partially confirmed

Results arrive in your Superpower dashboard with measured values and reference ranges. The care team can explain the markers; review clinical decisions with your clinician. Confirm result timing before booking.

Panel-specific source · Source dated September 8, 2026

Under the hood

Follow the Evidence.

Every published claim should trace to a dated source. Missing evidence remains visible instead of being filled with assumptions.

Source 1Recorded for this record. Last source check September 8, 2026.View source
Source 2Recorded for this record. Last source check September 8, 2026.View source
Source 3Recorded for this record. Last source check September 8, 2026.View source
Source 4Recorded for this record. Last source check September 8, 2026.View source
Source 5Recorded for this record. Last source check September 8, 2026.View source
Source 6Recorded for this record. Last source check September 8, 2026.View source
Source 7Recorded for this record. Last source check September 8, 2026.View source
Source 8Recorded for this record. Last source check September 8, 2026.View source

True total cost

The Price. Plus the Details.

Pricing for Methylation Panel
ItemCurrent disclosed priceNote
Panel$149Verify the checkout total, shipping, and collection fees before ordering.
Checkout feesNone addedSuperpower's fee record shows no order, draw or physician fee for this test.
Total at checkout$149The listed price, with no added fees on record.
HSA/FSA paymentNot confirmedHSA/FSA payment eligibility has not been confirmed from provider documentation.
Optional servicesAt-home phlebotomist visit, $99Only if you choose it. Not included in the total. Checked September 30, 2026. Source

Price status. This record shows disclosed pricing. Checkout costs can change and should be verified before purchase.

Your data

Your Data. Your Questions.

Privacy details are scored only when source documentation is available. Unconfirmed retention, deletion, research use, or marketing practices remain unconfirmed.

Reading the labels

What Has Been Checked?

Source collected

Evidence labels stay separate from the Test Grade. They show how much source support exists for the evaluation.

The balance

The Strengths. The Tradeoffs.

Strengths

  • Combines vitamin B12 with methylmalonic acid and homocysteine for complementary information about B-vitamin status.
  • Includes vitamin B6 in both regional versions and RBC folate in the national version.
  • Online ordering connects to professional blood collection at Quest Diagnostics or BioReference laboratories.

Watch-outs

  • RBC folate is included nationally but omitted from the New York/New Jersey version. Confirm the version available for your address.
  • The test costs $149 nationally or $239 in New York and New Jersey. Annual memberships are separately displayed at $199 or $399. Membership applicability, the complete unavoidable total and product-specific refunds remain unconfirmed.
  • Ask about preparation, collection frequency and result timing before booking. An exact number of draws and a turnaround range have not been confirmed.
  • This panel measures blood markers rather than MTHFR gene variants. It does not establish the cause of fatigue, mood changes or cardiovascular risk by itself.
  • Review abnormal results with a clinician before changing supplements or treatment. Complete assay performance, report thresholds and product-specific sample handling remain unconfirmed.

Take it with you

The Test Truth Card

The key facts from this review in one compact card.

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Verification History

September 8, 2026Recorded source date.Source collected

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