Skip to content
Find My Test

ApoE Genetic Test for Alzheimer’s and Cardiac Risk Cheek Swab from Life Extension Lab Testing

Labbrary Test GradeUseful
Your Fit Score
Not calculated

Answer five questions to see how this panel matches your goals, budget, collection preferences, access, and support needs.

Calculate my fit

Labbrary's review, Fit Score, and basic comparison are free. The provider's panel, shipping, collection, clinician review, and other services are separate. About 2 minutes. No account required.

A direct-to-consumer genetic test that identifies which ApoE variants (E2, E3, or E4) you carry, linking them to Alzheimer's and heart-disease risk with an allele-specific risk table.

Current price
$149
Sample
Swab
Turnaround
14 to 21 days
Access
At Home, Mail In, Order Online
Evidence & Key Facts
Source collectedLast source check September 17, 2026

Evidence basis. This named result reflects the sources and verification evidence listed on this page as of the date shown.

Best for

Brain Health, Genetic Risk

Standout strength

Direct APOE E2/E3/E4 genotyping from an at-home cheek swab - no lab visit needed.

Important watch-out

APOE is a single genetic risk factor - it cannot diagnose Alzheimer's or predict with certainty whether you will develop it.

ApoE Genetic Test for Alzheimer’s and Cardiac Risk Cheek Swab from Life Extension Lab Testing
Labbrary Test GradeUseful
Your Fit Score
Not calculated

Answer five questions to see how this panel matches your goals, budget, collection preferences, access, and support needs.

Calculate my fit

Labbrary's review, Fit Score, and basic comparison are free. The provider's panel, shipping, collection, clinician review, and other services are separate. About 2 minutes. No account required.

A direct-to-consumer genetic test that identifies which ApoE variants (E2, E3, or E4) you carry, linking them to Alzheimer's and heart-disease risk with an allele-specific risk table.

Current price
$149
Sample
Swab
Turnaround
14 to 21 days
Access
At Home, Mail In, Order Online
Evidence & Key Facts
Source collectedLast source check September 17, 2026

Evidence basis. This named result reflects the sources and verification evidence listed on this page as of the date shown.

Best for

Brain Health, Genetic Risk

Standout strength

Direct APOE E2/E3/E4 genotyping from an at-home cheek swab - no lab visit needed.

Important watch-out

APOE is a single genetic risk factor - it cannot diagnose Alzheimer's or predict with certainty whether you will develop it.

Labbrary+

The Test Grade. The Reason Behind It.

Potentially useful for the right buyer, with meaningful evidence, coverage, transparency, access, cost, terms, or privacy tradeoffs to review.

A lower grade does not mean a panel is a bad personal fit. Your Fit Score can be higher when its purpose, price, sample, access, or support matches what you need.

Explore the Full Methodology
Labbrary Test GradeUseful

Next step

Check the panel or research the provider

Prices, availability, and ordering requirements can change. Confirm the current details before purchasing.

Scope, both directions

Inside the Panel. Beyond the Name.

Named measurements

  • Apolipoprotein E (ApoE) E2/E3/E4 genotype

Measured categories and focus areas

  • Genetics
  • Brain Health
  • Genetic Risk
  • Heart Health

Important limits and omissions

Additional exclusions have not been confirmed for this test. Compare the named biomarkers with the markers you want before ordering.

Pre-Buy Audit · Labbrary+

1broader panel with a lower listed price lists every biomarker on this one.

Unlock the 1 Panel

Included with Labbrary+. Members see each panel by name and listed price, and can audit them in one click.

Counted among one-time at-home listings with a published price, matched by published biomarker names. That doesn’t mean the tests are equivalent. Updated October 3, 2026.

The full breakdown

Eight Dimensions.
One Named Result.

Open any row for the reasoning and evidence behind the named result.

The product page documents an at-home cheek swab that determines which ApoE variants (E2, E3, or E4) the customer carries, and the page footer names National Diagnostics, Inc. as the laboratory. The assay method and analytical performance figures such as sensitivity or specificity are not published, so measurement accuracy cannot be independently confirmed.

APOE is the strongest common genetic risk factor for late-onset Alzheimer's disease, and the product page explicitly frames the test around Alzheimer's and cardiac risk. The allele-specific content matches the panel's stated purpose directly, with the page cautioning that genetic risk is probabilistic rather than diagnostic.

The test covers the three ApoE alleles (E2, E3, E4) that define Alzheimer's genetic risk tiers. It is a single-gene risk test: it includes no amyloid or tau blood biomarkers and no broader cognitive measures, so it captures inherited risk only.

The price is a clearly stated $149 one-time sale purchase with no membership required. Shipping or additional fees are not stated, and HSA or FSA eligibility is not addressed on the product page.

The page includes an allele-specific risk table explaining what each ApoE variant means for Alzheimer's and cardiac risk, and frames the results as probabilistic risk rather than a diagnosis. No clinician consultation or individualized follow-up service is described.

The exact first-party product page states the price, the variants tested, the 2 to 3 week turnaround, and the Pennsylvania exclusion. The assay method, analytical performance, and genetic-data handling details are not disclosed, which limits full transparency.

The test is ordered online and collected at home with a cheek swab, with results in 2 to 3 weeks from specimen receipt. It is not available in Pennsylvania; no other state exclusions are stated.

Results are delivered by mail, email, or fax per the product page. How genetic data is stored, how long it is retained, and whether it is shared with third parties are not stated, leaving the privacy picture incomplete.

Under the hood

Follow the Evidence.

Every published claim should trace to a dated source. Missing evidence remains visible instead of being filled with assumptions.

Source 1Recorded for this record. Last source check September 17, 2026.View source

True total cost

The Price. Plus the Details.

Pricing for ApoE Genetic Test for Alzheimer’s and Cardiac Risk Cheek Swab
ItemCurrent disclosed priceNote
Panel$149Verify the checkout total, shipping, and collection fees before ordering.
Checkout feesNone addedLife Extension Lab Testing's fee record shows no order, draw or physician fee for this test.
Total at checkout$149The listed price, with no added fees on record.
HSA/FSA paymentNot confirmedHSA/FSA payment eligibility has not been confirmed from provider documentation.
Optional servicesNot confirmedClinician review, subscriptions, and retesting discounts are listed only when documented.

Price status. This record shows disclosed pricing. Checkout costs can change and should be verified before purchase.

Your data

Your Data. Your Questions.

Privacy details are scored only when source documentation is available. Unconfirmed retention, deletion, research use, or marketing practices remain unconfirmed.

Reading the labels

What Has Been Checked?

Source collected

Evidence labels stay separate from the Test Grade. They show how much source support exists for the evaluation.

The balance

The Strengths. The Tradeoffs.

Strengths

  • Direct APOE E2/E3/E4 genotyping from an at-home cheek swab - no lab visit needed.
  • Covers both Alzheimer's and cardiac risk relevance in a single test.
  • Allele-specific risk table explains what each variant means in plain language.
  • One-time $149 purchase with no membership or subscription.

Watch-outs

  • APOE is a single genetic risk factor - it cannot diagnose Alzheimer's or predict with certainty whether you will develop it.
  • Includes no amyloid or tau blood biomarkers.
  • The assay method and analytical performance figures are not published.
  • Not available in Pennsylvania; genetic-data storage and sharing terms are not stated.

Take it with you

The Test Truth Card

The key facts from this review in one compact card.

Keep deciding

APOE & MTHFR Genetic Test

RxHomeTest

Strong

An at-home saliva test analyzing ApoE, MTHFR, and KLOTHO gene variants tied to cognitive aging, with results delivered within days of the lab receiving the sample.

Price
$129.99
Turnaround
7 days
Labbrary+

Marker by Labcorp™ Genetic Health Panel

Labcorp OnDemand

Strong

Examines measurements related to genetic risk and heart health so results can be reviewed in the appropriate health context.

Price
$499
Turnaround
21 days
Labbrary+
Compare

Verification History

September 17, 2026Recorded source date.Source collected

Affiliate disclosure. Some outbound links may earn Labbrary a commission. Affiliate relationships never influence a Test Grade.

LABBRARY / FREE NEWSLETTER

Keep Your
Curiosity Informed.

New tests. Meaningful updates. Smarter questions to ask before you buy. Get Labbrary's free newsletter in your inbox.

Free to join. No account needed. Privacy Policy